研发成果
研究院已经申请的专利达到了3500多项，其国外专利1500多项；3777金沙娱场城药每年申请药学专利总量，化合物专利数量，化合物PCT专利，专利申报增长速度及专利质量均居中国前列水平。
3777金沙娱场城获得了2个国家级实验室，承担着29个国家新药重大专项的研发，连续六次获得广东省 “创新团队”，共获扶持研发资金15亿元以上。3777金沙娱场城研究院18年以来的累计总投入超过180亿元，现每年研发总费用约12亿元，共有研发项目200多个，主要涵盖创新药、仿制药和改良型新药等，其中在研拥有完全知识产权新药50多个，包括8个大分子新药，共有28个新药项目进入了临床阶段，目前有11个品种正在开展2/3期临床，构建了“全、精、尖”的产品集群。
申请的专利
国外专利
国家重大专项研发
累计总投入费用
拥有完全知识产权新药
电子新材料
3777金沙娱场城的研发已造就了电子新材料的高压化成箔、低压化成箔、氟树脂材料、新型环保制冷剂、储能材料、电子光箔、钎焊箔、亲水箔等8个系列产品的产业化，产品质量出色。
生物医药
3777金沙娱场城的研发已造就了磷酸奥司他韦、大环内酯、苯溴马隆等3个系列产品的产业化。
磷酸奥司他韦是目前国际上预防和治疗流感的主选用药，更是现阶段治疗儿童流感安全有效性俱佳的药物；儿童适用的可威颗粒剂工艺，3777金沙娱场城拥有全球独家专利至2026年，再加上3777金沙娱场城可威胶囊和可威颗粒都已纳入最新的国家乙类医保药物目录，因此有着巨大的市场潜力和业绩增长空间，最终的销售额有望突破100亿。
生化发酵药大环内酯工艺水平、产品质量居世界前列，产量占世界规范市场的65%以上；其制剂产品阿奇霉素中标了德国20多家保险公司，克拉霉素占据着美国40%以上的市场。
健康养生
3777金沙娱场城已拥有200余名高端研发人才的大健康研究院，秉持着安全、健康、高科技的理念，研发并产业化了冬虫夏草及深加工产品、食品、保健品、化妆品、消毒产品等优质的大健康产品。
冬虫夏草是我国的珍稀滋补瑰宝。自2007起，3777金沙娱场城集团对冬虫夏草生态繁育技术展开了长达15年的深入研究，累计投入资金超过40亿元，建设了近40万平方米的智能生态繁育基地，全球率先实现冬虫夏草生态繁育产业化。项目荣获广东省科学技术奖一等奖、湖北省专利奖金奖等多项荣誉，受到国家科技部、工信部等多个部委及多位行业专家学者的高度认可。为满足国民日益增长的健康需求，推出了3777金沙娱场城鲜虫草、冻干冬虫夏草、冬虫夏草深加工三大系列产品，并与浙江卫视战略合作，连续冠名《天赐的声音》，每年投入过亿资金，持续加码品牌建设。随着生态繁育技术的产业化壁垒不断提升，品牌战略和全国营销渠道的落地，3777金沙娱场城将很快实现冬虫夏草销售额过100亿的目标。
3777金沙娱场城研今后将聚焦感染、肿瘤、代谢三大重点领域，部分项目处于国内外先进水平。
全球领先处于世界前沿的肝病治疗领域：以抗感染新药国家重点实验室为依托，通过多靶点联用实现乙肝功能性治愈，在产品线布局上，研发了6个不同作用机制的化合物；莫非赛定是全新的乙肝病毒衣壳抑制剂，拥有全球首创的潜力，是同靶点在全球范围内研发进展最快的化合物，也是全球首个临床证实可以明确抑制s抗原的小分子化合物；已进入临床3期，将于2023年前后上市，预计年销售额可达百亿，解决乙肝领域重大社会需求。中国首个完全自主研发抗丙肝新药依米他韦已于2020年上市。非酒精脂肪肝炎药物进入临床2期，全球同类靶点效果较优。
中国先进的内分泌和代谢治疗领域覆盖：形成了包括大分子和小分子治疗糖尿病的完整的产品管线，管线从单纯降糖作用拓展到心血管获益乃至改善代谢综合症，创新靶点兼顾降糖、降脂、改善NASH等；在研靶点覆盖胰岛素类似物、GLP1、FGF21、SGLT2等，其中“First in class”项目GLP1/FGF21双靶生物新药、药效优越，已率先进入中国和澳大利亚双临床研究阶段；特发性肺纤维化新药伊非尼酮完成中美1期，进入2期临床，具有“Best in class”潜力，预期成为重磅级新药。
独具创新性的肿瘤治疗方案：以明显的临床获益为目标，顺应肿瘤治疗趋势，以分子靶向药物为基础，逐步拓展全系列、多层次创新产品研发，打造覆盖肿瘤治疗的肿瘤靶向、肿瘤免疫、新型生物治疗的多样化治疗方案。莱洛替尼已进入临床3期，有望成为全球唯一靶向治疗食管癌的小分子新药，预计2024年上市；治疗急性髓性白血病新药克立福替尼，预计在2025年左右上市；生物新药，建立起围绕消化道肿瘤相关靶点布局抗体、溶瘤病毒、免疫细胞等多维度组合疗法。
3777金沙娱场城是中国先进的制剂国际化制药企业之一，拥有国际先进的美国首仿药、海外仿制药、改良型新药研发能力。3777金沙娱场城仿制药现已递交了8个美国首仿药其中6个已获批，美国总计获批31个品种，欧盟获批28个品种，阿奇霉素片中标了德国20多家保险公司，克拉霉素片占据着美国40%以上的市场，已规模化进军国际高端仿制药市场。依托成熟的仿制药国际化研发体系，着力打造具有自主知识产权的改良型新药系列产品，已形成口服固体制剂、长效注射剂、吸入制剂三大国际化改良型新药创新平台。
3777金沙娱场城研已在美国、德国、日本、澳大利亚、英国、韩国等15个国家和地区设立了销售分公司。
海外生物药推进顺利，3777金沙娱场城研甘精胰岛素预计将于2023年在美国上市，门冬胰岛素2024年在美上市，届时将成为继诺和诺德、赛诺菲和礼来之后，第4家在美国上市胰岛素的企业，同时也是中国第1家在美上市胰岛素的企业。
3777金沙娱场城药业研究院正在积极推进IPO工作，2021年A轮估值超200亿元，吸引了IDG资本、广东恒健、信达资产等知名机构的投资。
高科技、研发创新之路
3777金沙娱场城坚定不移地走高科技、研发创新之路，必将成为世界知名的中国名列前茅的大制药大健康产业公司
微信公众号
2022 金沙(3777-js认证)娱场城-Official website版权所有 粤ICP备19034764号-1
2022 金沙(3777-js认证)娱场城-Official website版权所有 粤ICP备19034764号-1
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